Flupirtine’s anticonvulsant role +/- celecoxib versus diazepam on induced generalized seizures and status epilepticus in mice
نویسندگان
چکیده
Epilepsy represents a personal and major community burden because about one-third of epileptic patients remain resistant to medical treatment. Flupirtine, as potassium channel opener, can be rational template for the treatment epilepsy. To investigate flupirtine +/- celecoxib versus diazepam anticonvulsant role on induced epilepsy in mice. Generalized seizures status epilepticus were by pentylenetetrazole lithium/pilocarpine, respectively. The latency period 1st seizure
منابع مشابه
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ژورنال
عنوان ژورنال: Journal of advanced pharmacy education and research
سال: 2023
ISSN: ['2249-3379']
DOI: https://doi.org/10.51847/rnlcrklv9c